Poorly Water-Soluble APIs: Identify the Most Promising Formulation Strategies
03 Nov 2026
Poor water solubility remains one of the major challenges in pharmaceutical development. During the preformulation stage, researchers must rapidly identify the most suitable approaches to improve the dissolution of their drug candidates while working with limited quantities of active pharmaceutical ingredients (APIs). Between tight timelines, scarce compounds, and the need to make informed decisions early in development, every milligram of API counts.